Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy.
Fourier transform infrared spectroscopy (FTIR), circular dichroism (CD), and electron microscopy (EM) have been used simultaneously to follow the temperature-induced formation of amyloid fibrils by bovine insulin at acidic pH. The FTIR and CD data confirm that, before heating, insulin molecules in s...
Главные авторы: | Bouchard, M, Zurdo, J, Nettleton, E, Dobson, C, Robinson, C |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2000
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