Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

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Avian influenza A (H5N1) viruses cause severe disease in humans, but the basis for their virulence remains unclear. In vitro and animal studies indicate that high and disseminated viral replication is important for disease pathogenesis. Laboratory experiments suggest that virus-induced cytokine dysr...

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Dettagli Bibliografici
Autori principali: De Jong, M, Simmons, C, Thanh, T, Hien, V, Smith, G, Chau, T, Hoang, D, Chau, N, Khanh, T, Dong, V, Qui, P, Cam, B, Ha, D, Guan, Y, Peiris, J, Chinh, N, Hien, T, Farrar, J
Natura: Journal article
Lingua:English
Pubblicazione: Nature 2006

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