Streamlined synthesis of taxol analogues

<p>This thesis centres on the synthesis of taxol analogues via late-stage hydroxylation with P450 enzymes. To accomplish this, the taxane core, specifically taxa-4(5),11(12)-dien-2-one, was synthesised by classical synthetic methods, and subsequently oxidised using P450<sub>BM3</sub&g...

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Bibliographic Details
Main Author: Rodriguez, P
Other Authors: Robertson, J
Format: Thesis
Language:English
Published: 2017
Subjects: