Streamlined synthesis of taxol analogues
<p>This thesis centres on the synthesis of taxol analogues via late-stage hydroxylation with P450 enzymes. To accomplish this, the taxane core, specifically taxa-4(5),11(12)-dien-2-one, was synthesised by classical synthetic methods, and subsequently oxidised using P450<sub>BM3</sub&g...
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| Format: | Thesis |
| Language: | English |
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2017
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