Maternal circulating syncytiotrophoblast-derived extracellular vesicles contain biologically active 5'-tRNA halves

The placenta releases syncytiotrophoblast-derived extracellular vesicles (STB-EV) into the maternal circulation throughout gestation. STB-EV dependent signalling is believed to contribute to the widespread maternal adaptive physiological changes seen in pregnancy. Transfer RNA (tRNA) halves have bee...

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Bibliographic Details
Main Authors: Cooke, W, Cribbs, A, Zhang, W, Kandzija, N, Motta-Mejia, C, Dombi, E, Ri, R, Cerdeira, A, Redman, C, Vatish, M
Format: Journal article
Language:English
Published: Elsevier 2019