Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Up to 10% of cases of gastric cancer are familial, but so far, only mutations in CDH1 have been associated with gastric cancer risk. To identify genetic variants that affect risk for gastric cancer, we collected blood samples from 28 patients with hereditary diffuse gastric cancer (HDGC) not associa...

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Κύριοι συγγραφείς: Sahasrabudhe, R, Lott, P, Bohorquez, M, Toal, T, Estrada, A, Suarez, J, Brea-Fernández, A, Cameselle-Teijeiro, J, Pinto, C, Ramos, I, Mantilla, A, Prieto, R, Corvalan, A, Norero, E, Alvarez, C, Tapia, T, Carvallo, P, Gonzalez, L, Cock-Rada, A, Solano, A, Neffa, F, Della Valle, A, Yau, C, Soares, G, Borowsky, A, Hu, N, He, L, Han, X, Latin American Gastric Cancer Genetics Collaborative Group, Taylor, P, Goldstein, A, Torres, J, Echeverry, M, Ruiz-Ponte, C, Teixeira, M, Carvajal Carmona, L
Μορφή: Journal article
Γλώσσα:English
Έκδοση: AGA Institute 2016

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