Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer

Up to 10% of cases of gastric cancer are familial, but so far, only mutations in CDH1 have been associated with gastric cancer risk. To identify genetic variants that affect risk for gastric cancer, we collected blood samples from 28 patients with hereditary diffuse gastric cancer (HDGC) not associa...

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Main Authors: Sahasrabudhe, R, Lott, P, Bohorquez, M, Toal, T, Estrada, A, Suarez, J, Brea-Fernández, A, Cameselle-Teijeiro, J, Pinto, C, Ramos, I, Mantilla, A, Prieto, R, Corvalan, A, Norero, E, Alvarez, C, Tapia, T, Carvallo, P, Gonzalez, L, Cock-Rada, A, Solano, A, Neffa, F, Della Valle, A, Yau, C, Soares, G, Borowsky, A, Hu, N, He, L, Han, X, Latin American Gastric Cancer Genetics Collaborative Group, Taylor, P, Goldstein, A, Torres, J, Echeverry, M, Ruiz-Ponte, C, Teixeira, M, Carvajal Carmona, L
פורמט: Journal article
שפה:English
יצא לאור: AGA Institute 2016

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