Role of N-glycan trimming in the folding and secretion of the pestivirus protein E(rns)

N-glycosylation inhibitors have antiviral effect against bovine viral diarrhea virus. This effect is associated with inhibition of the productive folding pathway of E1 and E2 envelope glycoproteins. E(rns) is the third pestivirus envelope protein, essential for virus infectivity. The protein is heav...

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Bibliographic Details
Main Authors: Branza-Nichita, N, Lazar, C, Dwek, R, Zitzmann, N
Format: Journal article
Language:English
Published: Elsevier 2004