Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism
To explore the functions of RUNX3 single nucleotide polymorphisms (SNPs) associated with ankylosing spondylitis (AS).Individual SNP associations were evaluated in 4230 UK cases. Their effects on transcription factor (TF) binding, transcription regulation, chromatin modifications, gene expression and...
Главные авторы: | Vecellio, M, Cortes, A, Roberts, A, Ellis, J, Cohen, C, Knight, J, Brown, M, Bowness, P, Wordsworth, B |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
BMJ Publishing Group
2018
|
Схожие документы
-
FROM SNPs TO FUNCTION: TRANSCRIPTIONAL REGULATION OF RUNX3 IN ANKYLOSING SPONDYLITIS
по: Vecellio, M, и др.
Опубликовано: (2014) -
Functional genomic analysis of a RUNX3 polymorphism associated with ankylosing spondylitis
по: Vecellio, M, и др.
Опубликовано: (2021) -
The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression
по: Vecellio, M, и др.
Опубликовано: (2015) -
RUNX3 and T-Bet in immunopathogenesis of ankylosing spondylitis—novel targets for therapy?
по: Vecellio, M, и др.
Опубликовано: (2019) -
Disruption of c-MYC binding and chromosomal looping involving genetic variants associated with ankylosing spondylitis upstream of the RUNX3 promoter
по: Cohen, CJ, и др.
Опубликовано: (2022)