Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism

To explore the functions of RUNX3 single nucleotide polymorphisms (SNPs) associated with ankylosing spondylitis (AS).Individual SNP associations were evaluated in 4230 UK cases. Their effects on transcription factor (TF) binding, transcription regulation, chromatin modifications, gene expression and...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Vecellio, M, Cortes, A, Roberts, A, Ellis, J, Cohen, C, Knight, J, Brown, M, Bowness, P, Wordsworth, B
Format: Journal article
Sprache:English
Veröffentlicht: BMJ Publishing Group 2018