Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism

To explore the functions of RUNX3 single nucleotide polymorphisms (SNPs) associated with ankylosing spondylitis (AS).Individual SNP associations were evaluated in 4230 UK cases. Their effects on transcription factor (TF) binding, transcription regulation, chromatin modifications, gene expression and...

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Detalhes bibliográficos
Principais autores: Vecellio, M, Cortes, A, Roberts, A, Ellis, J, Cohen, C, Knight, J, Brown, M, Bowness, P, Wordsworth, B
Formato: Journal article
Idioma:English
Publicado em: BMJ Publishing Group 2018