Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.

Protein kinase autophosphorylation of activation segment residues is a common regulatory mechanism in phosphorylation-dependent signalling cascades. However, the molecular mechanisms that guarantee specific and efficient phosphorylation of these sites have not been elucidated. Here, we report on thr...

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Bibliographic Details
Main Authors: Pike, A, Rellos, P, Niesen, F, Turnbull, A, Oliver, A, Parker, SA, Turk, B, Pearl, L, Knapp, S
Format: Journal article
Language:English
Published: 2008