Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection

Reprogramming lipid metabolic pathways is a critical feature of activating immune responses to infection. However, how these reconfigurations occur is poorly understood. Our previous screen to identify cellular deubiquitylases (DUBs) activated during influenza virus infection revealed Usp25 as a pro...

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Bibliographic Details
Main Authors: Teo, QW, Wong, HH, Heunis, T, Stancheva, V, Hachim, A, Lv, H, Siu, L, Ho, J, Lan, Y, Mok, CKP, Ulferts, R, Sanyal, S
Format: Journal article
Language:English
Published: Cell Press 2023