Role of cathepsins in Mycobacterium tuberculosis survival in human macrophages

Cathepsins are proteolytic enzymes that function in the endocytic pathway, especially in lysosomes, where they contribute directly to pathogen killing or indirectly, by their involvement in the antigen presentation pathways. Mycobacterium tuberculosis (MTB) is a facultative intracellular pathogen th...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Pires, D, Marques, J, Pombo, J, Carmo, N, Bettencourt, P, Neyrolles, O, Lugo-Villarino, G, Anes, E
Format: Journal article
Język:English
Wydane: Nature Publishing Group 2016