A model for pathogen population structure with cross-protection depending on the extent of overlap in antigenic variant repertoires.
The persistence of discrete antigenic types among pathogens with multiple immunogenic loci can be explained by the action of immune-mediated competition. It has previously been shown that pathogen populations will self-organize into non-overlapping subsets of antigenic variants if cross-protection b...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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