Activated invariant NKT cells regulate osteoclast development and function.

Invariant NKT (iNKT) cells modulate innate and adaptive immune responses through activation of myeloid dendritic cells and macrophages and via enhanced clonogenicity, differentiation, and egress of their shared myeloid progenitors. Because these same progenitors give rise to osteoclasts (OCs), which...

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Bibliographic Details
Main Authors: Hu, M, Bassett, J, Danks, L, Howell, P, Xu, K, Spanoudakis, E, Kotsianidis, I, Boyde, A, Williams, G, Horwood, N, Roberts, I, Karadimitris, A
Format: Journal article
Language:English
Published: American Association of Immunologists 2011