Parkinson disease, LRRK2 and the endocytic-autophagic pathway.

Neurons are quiescent cells that survive for several decades, many times the turnover time of most organelles and proteins, and so with advancing age neurons become affected by degenerative diseases. Autophagy is thought to be an important cellular mechanism preventing cell degeneration in such long...

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Bibliographic Details
Main Authors: Alegre-Abarrategui, J, Wade-Martins, R
Format: Journal article
Language:English
Published: 2009