Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.

OBJECTIVE: Proteomic analysis has previously shown that activin A, a member of the transforming growth factor beta family, is produced by human articular cartilage. This study was undertaken to investigate whether activin A affects cartilage matrix catabolism and how its production is regulated. ME...

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Bibliografiska uppgifter
Huvudupphovsmän: Alexander, S, Watt, F, Sawaji, Y, Hermansson, M, Saklatvala, J
Materialtyp: Journal article
Språk:English
Publicerad: 2007