TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent and TCR-independent mechanisms. Here, we examined the impact of combinations of TCR-dependent and TCR-independent signals in human CD8+ MAIT cells. TCR-independent activation of these MAIT cells from...

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Bibliographic Details
Main Authors: Leng, T, Delowar Akther, H, Hackstein, C-P, Powell, K, King, T, Friedrich, M, Christoforidou, Z, McCuaig, S, Neyazi, M, Arancibia-Carcamo, CV, Hagel, J, Powrie, F, Oxford IBD Investigators, Sanches Peres, R, Millar, V, Ebner, D, Lamichhane, R, Ussher, J, Hinks, TSC, Marchi, E, Willberg, C, Klenerman, P
Format: Journal article
Language:English
Published: Elsevier 2019

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