The relevance in adults of air-flow obstruction, but not of mucus hypersecretion, to mortality from chronic lung disease. Results from 20 years of prospective observation.

From 1954 to 1961, pulmonary function was assessed in 2,718 British men by forced expiratory maneuvers, and mucus hypersecretion and smoking habits were assessed by questionnaires. In 20 to 25 yr of follow-up, 104 men (all of whom had smoked) died of chronic obstructive pulmonary disease (COPD). The...

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Bibliographic Details
Main Authors: Peto, R, Speizer, F, Cochrane, A, Moore, F, Fletcher, C, Tinker, C, Higgins, I, Gray, R, Richards, S, Gilliland, J, Norman-Smith, B
Format: Journal article
Language:English
Published: 1983