Total synthesis of the Fusarium toxin equisetin.
A short stereoselective synthesis of the Fusarium toxin equisetin, a potent inhibitor of HIV-1 integrase enzyme is described, using as the key step a stereoselective intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioeste...
Prif Awduron: | , , , |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2005
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