Total synthesis of the Fusarium toxin equisetin.
A short stereoselective synthesis of the Fusarium toxin equisetin, a potent inhibitor of HIV-1 integrase enzyme is described, using as the key step a stereoselective intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioeste...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2005
|
| _version_ | 1826273877816246272 |
|---|---|
| author | Burke, LT Dixon, D Ley, S Rodríguez, F |
| author_facet | Burke, LT Dixon, D Ley, S Rodríguez, F |
| author_sort | Burke, LT |
| collection | OXFORD |
| description | A short stereoselective synthesis of the Fusarium toxin equisetin, a potent inhibitor of HIV-1 integrase enzyme is described, using as the key step a stereoselective intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester. |
| first_indexed | 2024-03-06T22:34:54Z |
| format | Journal article |
| id | oxford-uuid:598e4883-14ad-43d4-a70c-afa3016cef1e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:34:54Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:598e4883-14ad-43d4-a70c-afa3016cef1e2022-03-26T17:10:26ZTotal synthesis of the Fusarium toxin equisetin.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:598e4883-14ad-43d4-a70c-afa3016cef1eEnglishSymplectic Elements at Oxford2005Burke, LTDixon, DLey, SRodríguez, FA short stereoselective synthesis of the Fusarium toxin equisetin, a potent inhibitor of HIV-1 integrase enzyme is described, using as the key step a stereoselective intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester. |
| spellingShingle | Burke, LT Dixon, D Ley, S Rodríguez, F Total synthesis of the Fusarium toxin equisetin. |
| title | Total synthesis of the Fusarium toxin equisetin. |
| title_full | Total synthesis of the Fusarium toxin equisetin. |
| title_fullStr | Total synthesis of the Fusarium toxin equisetin. |
| title_full_unstemmed | Total synthesis of the Fusarium toxin equisetin. |
| title_short | Total synthesis of the Fusarium toxin equisetin. |
| title_sort | total synthesis of the fusarium toxin equisetin |
| work_keys_str_mv | AT burkelt totalsynthesisofthefusariumtoxinequisetin AT dixond totalsynthesisofthefusariumtoxinequisetin AT leys totalsynthesisofthefusariumtoxinequisetin AT rodriguezf totalsynthesisofthefusariumtoxinequisetin |