The genetics of NOD-like receptors in Crohn's disease.

The first Crohn's disease (CD) susceptibility gene identified was CARD15, which is a member of the emerging NOD-like receptor (NLR) family. These function as intracellular cystosolic pattern recognition receptors (PRRs) and play a central role in the innate immune response. We studied other mem...

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Detalles Bibliográficos
Autores principales: Cummings, JR, Cooney, R, Clarke, G, Beckly, J, Geremia, A, Pathan, S, Hancock, L, Guo, C, Cardon, L, Jewell, D
Formato: Journal article
Lenguaje:English
Publicado: 2010