The genetics of NOD-like receptors in Crohn's disease.

The first Crohn's disease (CD) susceptibility gene identified was CARD15, which is a member of the emerging NOD-like receptor (NLR) family. These function as intracellular cystosolic pattern recognition receptors (PRRs) and play a central role in the innate immune response. We studied other mem...

全面介紹

書目詳細資料
Main Authors: Cummings, JR, Cooney, R, Clarke, G, Beckly, J, Geremia, A, Pathan, S, Hancock, L, Guo, C, Cardon, L, Jewell, D
格式: Journal article
語言:English
出版: 2010