FRAGMATIC: A randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer

FRAGMATIC: A randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer

<p style="text-align:justify;"> <b>Background:</b> Venous thromboembolism (VTE) occurs when blood clots in the leg, pelvic or other deep vein (deep vein thrombosis) with or without transport of the thrombus into the pulmonary arterial circulation (pulmonary embolus). VTE...

Bibliográfalaš dieđut
Váldodahkkit:	Griffiths, G, Burns, S, Noble, S, Macbeth, F, Cohen, D, Maughan, T
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	BioMed Central 2009

Geahča maid

Interim safety data on the FRAGMATIC trial: a randomised phase III clinical trial investigating the effect of FRAGMin (R) added to standard therapy in patients with lung cancer
Dahkki: Macbeth, F, et al.
Almmustuhtton: (2009)

FRAGMATIC: A randomised phase III clinical trial investigating the effect of <b>fragm</b>in<sup>® </sup><b>a</b>dded to standard <b>t</b>herapy <b>i</b>n patients with lung <b>c</b>ancer
Dahkki: Macbeth Fergus R, et al.
Almmustuhtton: (2009-10-01)

Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily.
Dahkki: Dong Qian, et al.
Almmustuhtton: (2015-01-01)

Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/− cetuximab in oesophageal cancer
Dahkki: Crosby, T, et al.
Almmustuhtton: (2017)

Standard maintenance therapy versus local consolidative radiation therapy and standard maintenance therapy in 1–5 sites of oligometastatic non-small cell lung cancer: a study protocol of phase III randomised controlled trial
Dahkki: Sadhna Kannan, et al.
Almmustuhtton: (2021-03-01)

Utility of adding oesophageal to endobronchial endosonography when staging lung cancer: a randomised trial
Dahkki: Masahide Oki, et al.
Almmustuhtton: (2024-12-01)

Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS)
Dahkki: Sébastien Thureau, et al.
Almmustuhtton: (2021-02-01)

SCOPE1: a randomised phase II/III multicentre clinical trial of definitive chemoradiation, with or without cetuximab, in carcinoma of the oesophagus
Dahkki: Staffurth John N, et al.
Almmustuhtton: (2011-10-01)

The smoking cessation in pregnancy incentives trial (CPIT): study protocol for a phase III randomised controlled trial
Dahkki: Lesley Sinclair, et al.
Almmustuhtton: (2020-02-01)

Selection criteria for early breast cancer patients in the DBCG proton trial – The randomised phase III trial strategy
Dahkki: Line Bjerregaard Stick, et al.
Almmustuhtton: (2021-03-01)

Reporting of PPI and the MCID in phase III/IV randomised controlled trials—a systematic review
Dahkki: Joseph Brennan, et al.
Almmustuhtton: (2023-05-01)

TROG 18.01 phase III randomised clinical trial of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation: NINJA study protocol
Dahkki: Colin I Tang, et al.
Almmustuhtton: (2019-08-01)

Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trial.
Dahkki: Crosby, T, et al.
Almmustuhtton: (2013)

A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial
Dahkki: Peter Langhorne, et al.
Almmustuhtton: (2017-09-01)

Open versus laparoscopically-assisted oesophagectomy for cancer: a multicentre randomised controlled phase III trial - the MIRO trial
Dahkki: Msika Simon, et al.
Almmustuhtton: (2011-07-01)

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: Results of the Panitumumab, Irinotecan and Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)
Dahkki: Middleton, G, et al.
Almmustuhtton: (2013)

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan and Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).
Dahkki: Middleton, G, et al.
Almmustuhtton: (2013)

A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol
Dahkki: Pascoe, S, et al.
Almmustuhtton: (2016)

Tenecteplase versus alteplase for acute ischaemic stroke: a meta-analysis of phase III randomised trials
Dahkki: Yongjun Wang, et al.

Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: the phase 1/randomised phase 2 SCALOP-2 trial
Dahkki: Mukherjee, S, et al.
Almmustuhtton: (2024)

Rationale and design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III): a randomised, phase III, open-label, controlled trial
Dahkki: Bruce C V Campbell, et al.

Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer
Dahkki: Hurt, C, et al.
Almmustuhtton: (2017)

Trends in participant race and sex reporting in lung cancer phase III clinical trials
Dahkki: Faaiq N. Aslam, et al.
Almmustuhtton: (2023-09-01)

Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial
Dahkki: Garegrat, R, et al.
Almmustuhtton: (2024)

Effect of early palliative care for patients with glioblastoma (EPCOG): a randomised phase III clinical trial protocol
Dahkki: Stephanie Stock, et al.
Almmustuhtton: (2020-01-01)

Treatment outcomes in patients with seropositive versus seronegative rheumatoid arthritis in Phase III randomised clinical trials of tofacitinib
Dahkki: Peter Nash, et al.
Almmustuhtton: (2019-06-01)

Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial
Dahkki: Reema Garegrat, et al.
Almmustuhtton: (2024-07-01)

Fragility index of positive phase II and III randomised clinical trials of treatments for hepatocellular carcinoma (2002–2022)
Dahkki: Sabrina Sidali, et al.
Almmustuhtton: (2023-07-01)

Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial.
Dahkki: Mukherjee, S, et al.
Almmustuhtton: (2013)

Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial
Dahkki: Qi Wu, et al.
Almmustuhtton: (2024-09-01)

CONFIRM: a double-blind, placebo-controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: study protocol for a randomised controlled trial
Dahkki: Dean A. Fennell, et al.
Almmustuhtton: (2018-04-01)

Raltitrexed (Tomudex) versus standard leucovorin-modulated bolus 5-fluorouracil: Results from the randomised phase III Pan-European Trial in Adjuvant Colon Cancer 01 (PETACC-1).
Dahkki: Popov, I, et al.
Almmustuhtton: (2008)

Eligibility of patients with advanced non-small cell lung cancer for phase III chemotherapy trials
Dahkki: Dadasovich Ryan, et al.
Almmustuhtton: (2009-04-01)

OP0130 Mepolizumab for the treatment of patients with eosinophilic granulomatosis with polyangiitis: a phase iii randomised, placebo-controlled trial
Dahkki: Wechsler, M, et al.
Almmustuhtton: (2017)

Therapeutic serum level for adalimumab in rheumatoid arthritis: explorative analyses of data from a randomised phase III trial
Dahkki: Joseph Sexton, et al.
Almmustuhtton: (2024-11-01)

AVOID; a phase III, randomised controlled trial using indocyanine green for the prevention of anastomotic leakage in colorectal surgery
Dahkki: Hein Putter, et al.
Almmustuhtton: (2022-04-01)

Heartburn relief with bicarbonate-rich mineral water: results of the randomised, placebo-controlled phase-III trial STOMACH STILL
Dahkki: JOACHIM LABENZ, et al.
Almmustuhtton: (2023-08-01)

Efficacy and safety of iclepertin (BI 425809) in patients with schizophrenia: CONNEX, a Phase III randomised controlled trial programme
Dahkki: P. Falkai, et al.
Almmustuhtton: (2023-03-01)

Cabozantinib Versus Everolimus in Patients with Advanced Renal Cell Carcinoma: Results of a Randomised Phase III Trial (METEOR)
Dahkki: Toni Choueiri
Almmustuhtton: (2015-11-01)

Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial
Dahkki: Forder Peta M, et al.
Almmustuhtton: (2011-04-01)