Recombination-mediated escape from primary CD8+T cells in acute HIV-1 infection
Background: A major immune evasion mechanism of HIV-1 is the accumulation of non-synonymous mutations in and around T cell epitopes, resulting in loss of T cell recognition and virus escape.Results: Here we analyze primary CD8+ T cell responses and virus escape in a HLA B*81 expressing subject who w...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2014
|