Recombination-mediated escape from primary CD8+T cells in acute HIV-1 infection
Background: A major immune evasion mechanism of HIV-1 is the accumulation of non-synonymous mutations in and around T cell epitopes, resulting in loss of T cell recognition and virus escape.Results: Here we analyze primary CD8+ T cell responses and virus escape in a HLA B*81 expressing subject who w...
| Hlavní autoři: | , , , , , , , , , , |
|---|---|
| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
BioMed Central
2014
|