Recombination-mediated escape from primary CD8+T cells in acute HIV-1 infection
Background: A major immune evasion mechanism of HIV-1 is the accumulation of non-synonymous mutations in and around T cell epitopes, resulting in loss of T cell recognition and virus escape.Results: Here we analyze primary CD8+ T cell responses and virus escape in a HLA B*81 expressing subject who w...
| Main Authors: | , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
BioMed Central
2014
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