B cell antigen receptor signalling in the balance of tolerance and immunity.
The quantity and quality of signals from the B cell antigen receptor (BCR) drives the positive and negative selection of B lymphocytes and establishes the balance of tolerance and immunity. Experiments using immunoglobulin transgenic mice and mutations in key BCR signalling components have given ins...
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Detalhes bibliográficos
| Main Authors: |
Cornall, R,
Goodnow, C |
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| Formato: | Conference item
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| Publicado em: |
1998
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