B cell antigen receptor signalling in the balance of tolerance and immunity.

B cell antigen receptor signalling in the balance of tolerance and immunity.

The quantity and quality of signals from the B cell antigen receptor (BCR) drives the positive and negative selection of B lymphocytes and establishes the balance of tolerance and immunity. Experiments using immunoglobulin transgenic mice and mutations in key BCR signalling components have given ins...

Bibliografiset tiedot
Päätekijät:	Cornall, R, Goodnow, C
Aineistotyyppi:	Conference item
Julkaistu:	1998

Samankaltaisia teoksia

Role of Syk in B-cell development and antigen-receptor signaling.
Tekijä: Cornall, R, et al.
Julkaistu: (2000)

Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway.
Tekijä: Cornall, R, et al.
Julkaistu: (1999)

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance
Tekijä: Hodgson, R, et al.
Julkaistu: (2022)

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Tekijä: Rose Hodgson, et al.
Julkaistu: (2022-11-01)

The regulation of self-reactive B cells.
Tekijä: Cornall, R, et al.
Julkaistu: (1995)

Analysis of B-cell immune tolerance induction using transgenic mice.
Tekijä: Ferry, H, et al.
Julkaistu: (2004)

Mechanism of antigen binding to receptor antibody in B cell immunity and tolerance in vitro.
Tekijä: Feldmann, M
Julkaistu: (1973)

Single epitope multiple staining to detect ultralow frequency B cells.
Tekijä: Townsend, SE, et al.
Julkaistu: (2001)

Source data for: Hodgson et al, NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance, Communications Biology 2022
Tekijä: Hodgson, R, et al.
Julkaistu: (2022)

The essential role of DOCK8 in humoral immunity.
Tekijä: Randall, K, et al.
Julkaistu: (2010)

Tracing the action of IL-2 in tolerance to islet-specific antigen.
Tekijä: Liston, A, et al.
Julkaistu: (2007)

Role of antigen structure in the discrimination between tolerance and immunity by b cells.
Tekijä: Feldmann, M, et al.
Julkaistu: (1975)

Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults.
Tekijä: Ferry, H, et al.
Julkaistu: (2006)

Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.
Tekijä: Ferry, H, et al.
Julkaistu: (2007)

B-cell tolerance.
Tekijä: Ferry, H, et al.
Julkaistu: (2006)

Isotype control of B cell signaling.
Tekijä: Silver, K, et al.
Julkaistu: (2003)

Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.
Tekijä: Brink, R, et al.
Julkaistu: (1992)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival (vol 35, pg 3655, 2005)
Tekijä: Ferry, H, et al.
Julkaistu: (2005)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
Tekijä: Ferry, H, et al.
Julkaistu: (2005)

Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.
Tekijä: Siggs, O, et al.
Julkaistu: (2007)

Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247)
Tekijä: Ferry, H, et al.
Julkaistu: (2005)

B cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.
Tekijä: Taras Lyubchenko, et al.
Julkaistu: (2014-01-01)

Induction of immunity and tolerance in vitro by hapten protein conjugates. 3. Hapten inhibition studies of antigen binding to B cells in immunity and tolerance.
Tekijä: Feldmann, M
Julkaistu: (1972)

The advent of chimeric antigen receptor T Cell therapy in recalibrating immune balance for rheumatic autoimmune disease treatment
Tekijä: Qianyu Guo, et al.
Julkaistu: (2024-12-01)

Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance
Tekijä: Yannick D. Muller, et al.
Julkaistu: (2021-09-01)

The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse
Tekijä: Nikola Deretic, et al.
Julkaistu: (2021-07-01)

The impact of T cell intrinsic antigen adaptation on peripheral immune tolerance.
Tekijä: Nevil J Singh, et al.
Julkaistu: (2006-10-01)

B cell tolerance is intact in C1q deficient mice
Tekijä: Cutler, A, et al.
Julkaistu: (1999)

B cell receptor signaling strength modulates cancer immunity
Tekijä: Jian Ye, et al.
Julkaistu: (2022-03-01)

The cellular location of self-antigen determines the positive and negative selection of autoreactive B cells.
Tekijä: Ferry, H, et al.
Julkaistu: (2003)

Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.
Tekijä: Nijnik, A, et al.
Julkaistu: (2006)

Consequences of drug binding to immune receptors: Immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide
Tekijä: Werner J. Pichler
Julkaistu: (2013-12-01)

Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation.
Tekijä: Chakera, A, et al.
Julkaistu: (2011)

Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation
Tekijä: Chakera, A, et al.
Julkaistu: (2011)

Induction fo B cell tolerance by antigen specific T cell factor.
Tekijä: Feldman, M
Julkaistu: (1973)

Antigen receptor signaling: the Tuscan chronicles.
Tekijä: Baldari, C, et al.
Julkaistu: (2005)

Nanoparticle Platforms for Antigen-Specific Immune Tolerance
Tekijä: Edward B. Thorp, et al.
Julkaistu: (2020-05-01)

The immunological synapse balances T cell receptor signaling and degradation.
Tekijä: Lee, K, et al.
Julkaistu: (2003)

Differences in calcium requirements for B-cell tolerance and immunity.
Tekijä: Desaymard, C, et al.
Julkaistu: (1980)

Immune-mediated facial nerve paralysis in a myeloma patient post B-cell maturation antigen-targeted chimeric antigen receptor T cells
Tekijä: Yamini K. Kathari, et al.
Julkaistu: (2023-09-01)