B cell antigen receptor signalling in the balance of tolerance and immunity.

B cell antigen receptor signalling in the balance of tolerance and immunity.

The quantity and quality of signals from the B cell antigen receptor (BCR) drives the positive and negative selection of B lymphocytes and establishes the balance of tolerance and immunity. Experiments using immunoglobulin transgenic mice and mutations in key BCR signalling components have given ins...

Полное описание

Библиографические подробности
Главные авторы:	Cornall, R, Goodnow, C
Формат:	Conference item
Опубликовано:	1998

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