Pneumococcal capsule synthesis locus cps as evolutionary hotspot with potential to generate novel serotypes by recombination

Diversity of the polysaccharide capsule in Streptococcus pneumoniae -- main surface antigen and the target of the currently used pneumococcal vaccines -- constitutes a major obstacle in eliminating pneumococcal disease. Such diversity is genetically encoded by almost 100 variants of the capsule bios...

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Автори: Mostowy, R, Croucher, N, De Maio, N, Chewapreecha, C, Salter, S, Turner, P, Aanensen, D, Bentley, S, Didelot, X, Fraser, C
Формат: Journal article
Мова:English
Опубліковано: Oxford University Press 2017