Pneumococcal capsule synthesis locus cps as evolutionary hotspot with potential to generate novel serotypes by recombination
Diversity of the polysaccharide capsule in Streptococcus pneumoniae -- main surface antigen and the target of the currently used pneumococcal vaccines -- constitutes a major obstacle in eliminating pneumococcal disease. Such diversity is genetically encoded by almost 100 variants of the capsule bios...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2017
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