Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism

Mucosal-associated invariant T (MAIT) cells are an abundant human T cell subset with anti-microbial properties. They can respond to bacteria presented via antigen-presenting cells (APCs) such as macrophages, which present bacterially derived ligands from the riboflavin synthesis pathway on MR1. More...

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Bibliographic Details
Main Authors: Banki, Z, Krabbendam, L, Klaver, D, Leng, T, Kruis, S, Mehta, H, Müllauer, B, Orth-Höller, D, Stoiber, H, Willberg, C, Klenerman, P
Format: Journal article
Published: Wiley 2019