A novel inhibitor of complement C5 provides structural insights into activation

A novel inhibitor of complement C5 provides structural insights into activation

Abstract The complement system is a crucial part of innate immune defences against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a novel class of inhibitors f...

Bibliografske podrobnosti
Main Authors:	Reichhardt, M, Johnson, S, Tang, T, Morgan, T, Tebeka, N, Popitsch, N, Deme, J, Jore, M, Lea, S
Format:	Working paper
Izdano:	2019

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