Analysis and evaluation of channel models: simulations of alamethicin.

Alamethicin is an antimicrobial peptide that forms stable channels with well-defined conductance levels. We have used extended molecular dynamics simulations of alamethicin bundles consisting of 4, 5, 6, 7, and 8 helices in a palmitoyl-oleolyl-phosphatidylcholine bilayer to evaluate and analyze chan...

Full description

Bibliographic Details
Main Authors: Tieleman, D, Hess, B, Sansom, MS
Format: Journal article
Language:English
Published: 2002