Thymectomy and radiation-induced type 1 diabetes in nonlymphopenic BB rats.
Spontaneous type 1 diabetes in BB rats is dependent on the RT1(u) MHC haplotype and homozygosity for an allele at the Lyp locus, which is responsible for a peripheral T-lymphopenia. Genetic studies have shown that there are other, as yet unidentified, genetic loci contributing to diabetes susceptibi...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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