Thymectomy and radiation-induced type 1 diabetes in nonlymphopenic BB rats.

Spontaneous type 1 diabetes in BB rats is dependent on the RT1(u) MHC haplotype and homozygosity for an allele at the Lyp locus, which is responsible for a peripheral T-lymphopenia. Genetic studies have shown that there are other, as yet unidentified, genetic loci contributing to diabetes susceptibi...

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Detalhes bibliográficos
Main Authors: Ramanathan, S, Bihoreau, M, Paterson, A, Marandi, L, Gauguier, D, Poussier, P
Formato: Journal article
Idioma:English
Publicado em: 2002