Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

The syntheses and preliminary pharmacological characterisation of two novel cyclic phosphinic acid-containing amino acids designed as conformationally restricted analogues of the metabotropic glutamate receptor agonist AP4 (1) are reported.

Chi tiết về thư mục
Những tác giả chính:	Conway, S, Miller, J, Bond, A, Clark, B, Jane, D
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2002

Những quyển sách tương tự

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes
Bằng: Vladimir A. D’yakonov, et al.
Được phát hành: (2016-03-01)

Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors.
Bằng: Conway, S, et al.
Được phát hành: (2001)

Metabotropic glutamate receptor agonists for schizophrenia.
Bằng: Harrison, P
Được phát hành: (2008)

Synthesis of analogues of lycoperdic acid to probe glutamate receptors in the central nervous system
Bằng: Goundry, W, et al.
Được phát hành: (2003)

Synephrine Analogues as Glucocorticoid Receptor Agonists
Bằng: Eugenia Oleynik, et al.
Được phát hành: (2023-11-01)

Structural requirements for selective group III metabotropic glutamate receptor antagonists based on the phenylglycine nucleus.
Bằng: Jane, D, et al.
Được phát hành: (2002)

Novel phenylglycine analogues as potent and selective antagonists of group III mGlu receptors on neonatal rat primary afferent terminals.
Bằng: Miller, J, et al.
Được phát hành: (2000)

Computational study of synthetic agonist ligands of ionotropic glutamate receptors.
Bằng: Tino Wolter, et al.
Được phát hành: (2013-01-01)

Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals.
Bằng: Miller, J, et al.
Được phát hành: (2003)

The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.
Bằng: Bryan L Roth, et al.
Được phát hành: (2013-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
Được phát hành: (2014-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors.
Bằng: Tino Wolter, et al.
Được phát hành: (2014-01-01)

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.
Bằng: Bryan L Roth, et al.
Được phát hành: (2018-01-01)

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity
Bằng: Stanley, N.J., et al.
Được phát hành: (2010)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
Bằng: Veerapen, N, et al.
Được phát hành: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
Bằng: Veerapen, N, et al.
Được phát hành: (2011)

Synthesis and Biological Evaluation of Novel Biased Mu-Opioid Receptor Agonists
Bằng: Yanhao Guo, et al.
Được phát hành: (2024-06-01)

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
Bằng: Wenjing Sun, et al.
Được phát hành: (2023-06-01)

Binding site flexibility: Molecular simulation of partial and full agonists within a glutamate receptor
Bằng: Arinaminpathy, Y, et al.
Được phát hành: (2006)

Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.
Bằng: Arinaminpathy, Y, et al.
Được phát hành: (2006)

Effects of glutamate receptor agonists on the P13 auditory evoked potential and startle response in the rat
Bằng: Christen eSimon, et al.
Được phát hành: (2011-01-01)

Direct versatile route to conformationally constrained glutamate analogues
Bằng: Dyer, J, et al.
Được phát hành: (1998)

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
Bằng: Min-Juan Wang, et al.
Được phát hành: (2013-01-01)

Synthesis and biological evaluation of novel eunicellin analogues
Bằng: Gilmour, R, et al.
Được phát hành: (2005)

Inositol polyphosphates and analogues: synthesis & chemical biology
Bằng: Shipton, M
Được phát hành: (2021)

The synthesis and biological evaluation of novel eunicellin analogues
Bằng: Davidson, J, et al.
Được phát hành: (2004)

Synthesis and Biological Evaluation of New CRH Analogues
Bằng: Spyridon Papazacharias, et al.
Được phát hành: (2010-01-01)

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate
Bằng: Ewa Chmielewska, et al.
Được phát hành: (2019-08-01)

Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine
Bằng: Yongseok Kwon, et al.
Được phát hành: (2015-02-01)

Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptors.
Bằng: Thomas Blarre, et al.
Được phát hành: (2014-01-01)

Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues
Bằng: Juan Pablo Gonzalez-Gutierrez, et al.
Được phát hành: (2019-07-01)

Defense reaction induced by a metabotropic glutamate receptor agonist microinjected into the dorsal periaqueductal gray of rats
Bằng: M.L. Molchanov, et al.
Được phát hành: (1999-12-01)

The sigma1 receptor agonist enhances long-term depression caused by activation of metabotropic glutamate receptors in rat hippocampal neurons
Bằng: Pavel D. Rogozin, et al.
Được phát hành: (2018-12-01)

Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors
Bằng: Yasushi Matsumuraa, et al.
Được phát hành: (2004-03-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABAA-ρ Receptors
Được phát hành: (2014-01-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABA-ρ Receptors.
Được phát hành: (2014-01-01)

<it>In vivo </it>antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist - neurokinin 1 receptor antagonist chimera
Bằng: Guillemyn Karel, et al.
Được phát hành: (2012-01-01)

Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications
Bằng: M. Isabel Matheu, et al.
Được phát hành: (2019-08-01)

Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues
Bằng: Lucie Brulikova, et al.
Được phát hành: (2011-05-01)

Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex.
Bằng: Pei, Q, et al.
Được phát hành: (2004)