Interpretation of somatic POLE mutations in endometrial carcinoma

Interpretation of somatic POLE mutations in endometrial carcinoma

Pathogenic somatic missense mutations within the DNA polymerase epsilon (POLE) exonuclease domain define the important subtype of ultramutated tumours (‘POLE‐ultramutated’) within the novel molecular classification of endometrial carcinoma (EC). However, clinical implementation of this classifier re...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	León-Castillo, A, Britton, H, McConechy, MK, McAlpine, JN, Nout, R, Kommoss, S, Brucker, SY, Carlson, JW, Epstein, E, Rau, TT, Bosse, T, Church, DN, Gilks, CB
Format:	Journal article
Język:	English
Wydane:	Wiley 2020

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