The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology.

The neuropathological features of schizophrenia are suggestive of a developmentally induced impairment of synaptic connectivity. Semaphorin 3A (sema3A) might contribute to this process because it is a secreted chemorepellant which regulates axonal guidance. We have investigated sema3A in the cerebel...

Full description

Bibliographic Details
Main Authors: Eastwood, S, Law, A, Everall, I, Harrison, P
Format: Journal article
Language:English
Published: 2003