The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology.
The neuropathological features of schizophrenia are suggestive of a developmentally induced impairment of synaptic connectivity. Semaphorin 3A (sema3A) might contribute to this process because it is a secreted chemorepellant which regulates axonal guidance. We have investigated sema3A in the cerebel...
Main Authors: | Eastwood, S, Law, A, Everall, I, Harrison, P |
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Format: | Journal article |
Language: | English |
Published: |
2003
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