Directed synthesis of all four pure stereoisomers of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A
The first preparation of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A and its likewise naturally occurring minor atropisomer, in an atropisomerically pure form, is described. The synthesis succeeded by resolution of the already rotationally hindered, and thus atropo-diastereomer...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2016
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