Structural basis for the subunit assembly of the anaphase-promoting complex.

The anaphase-promoting complex or cyclosome (APC/C) is an unusually large E3 ubiquitin ligase responsible for regulating defined cell cycle transitions. Information on how its 13 constituent proteins are assembled, and how they interact with co-activators, substrates and regulatory proteins is limit...

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Dades bibliogràfiques
Autors principals: Schreiber, A, Stengel, F, Zhang, Z, Enchev, R, Kong, E, Morris, E, Robinson, C, da Fonseca, P, Barford, D
Format: Journal article
Idioma:English
Publicat: 2011