High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end stage liver disease

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end stage liver disease

The high replication and mutation rate of hepatitis C virus (HCV) results in a heterogeneous population of viral sequences in vivo. HCV replicates in the liver and infected hepatocytes occur as foci surrounded by uninfected cells that may promote compartmentalization of viral variants. Given recent...

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מידע ביבליוגרפי
Main Authors: Hedegaard, D, Tully, D, Rowe, I, Reynolds, G, Bean, D, Hu, K, Davis, C, Wilhelm, A, Ogilvie, C, Power, K, Tarr, A, Kelly, D, Allen, T, Balfe, P, McKeating, J
פורמט: Journal article
שפה:English
יצא לאור: Elsevier 2016

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