On the positional and orientational order of water and methanol around indole: a study on the microscopic origin of solubility

Although they are both highly polar liquids, there are a number of compounds, such as many pharmaceuticals, which show vastly different solubilities in methanol compared with water. From theories of the hydrophobic effect, it might be predicted that this enhanced solubility is due to association bet...

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Bibliographic Details
Main Authors: Henao, A, Johnston, A, Guàrdia, E, McLain, S, Pardo, L
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2016