Iridium-catalyzed reductive nitro-Mannich cyclization.
A new chemoselective reductive nitro-Mannich cyclization reaction sequence of nitroalkyl-tethered lactams has been developed. Relying on the rapid and chemoselective iridium(I)-catalyzed reduction of lactams to the corresponding enamine, subsequent nitro-Mannich cyclization of tethered nitroalkyl fu...
Autori principali: | , , , , |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Wiley
2015
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