Iridium-catalyzed reductive nitro-Mannich cyclization.

A new chemoselective reductive nitro-Mannich cyclization reaction sequence of nitroalkyl-tethered lactams has been developed. Relying on the rapid and chemoselective iridium(I)-catalyzed reduction of lactams to the corresponding enamine, subsequent nitro-Mannich cyclization of tethered nitroalkyl fu...

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Váldodahkkit: Gregory, A, Chambers, A, Hawkins, A, Jakubec, P, Dixon, D
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Wiley 2015