Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells.

We have applied the perforated patch whole-cell technique to beta cells within intact pancreatic islets to identify the current underlying the glucose-induced rhythmic firing of action potentials. Trains of depolarizations (to simulate glucose-induced electrical activity) resulted in the gradual (ti...

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Bibliographic Details
Main Authors: Göpel, S, Kanno, T, Barg, S, Eliasson, L, Galvanovskis, J, Renström, E, Rorsman, P
Format: Journal article
Language:English
Published: 1999