Contrasting effects of phosphatidylinositol 4,5-bisphosphate (PIP2 ) on cloned TMEM16A and TMEM16B channels
<h4>Background and Purpose</h4> <p>Ca2+-activated Cl- channels (CaCCs) are gated open by a rise in intracellular Ca2+ concentration ([Ca2+]i), typically provoked by activation of Gq-protein coupled receptors (GqPCR). GqPCR activation initiates depletion of plasmalemmal phosphatidy...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Published: |
Wiley
2017
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