Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.

OBJECTIVE: Five loci-the shared epitope (SE) of HLA--DRB1, the PTPN22 gene, a locus on 6q23, the STAT4 gene and a locus mapping to the TRAF1/C5 genetic region--have now been unequivocally confirmed as conferring susceptibility to RA. The largest single effect is conferred by SE. We hypothesized that...

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Những tác giả chính:	McClure, A, Lunt, M, Eyre, S, Ke, X, Thomson, W, Hinks, A, Bowes, J, Gibbons, L, Plant, D, Wilson, A, Marinou, I, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Worthington, J, Barton, A
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2009

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.

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